Baltic Summer School

PRELIMINARY PROGRAMME 2005

From Neuron to Neurology and Psychiatry

The Molecular, Genetic and Cellular Basis for Diseases in the Brain and Spinal Cord - Mechanisms and Emerging Technologies

University of Copenhagen, The Panum Institute
August 14 - August 26, 2005

Sunday 14.08.05

13:00 - 16:00Registration
16:00 - 17:00 Welcome addresses:
Director of the Baltic Summer School
Michael Illert, Kiel University
Dean of the Faculty of Health Sciences, University of Copenhagen
Ralf Hemmingsen
Dean of the Medical Faculty, Lund University
Jan Nilsson
Representative of the Government
To be determined
Organizers in Copenhagen: Welcome and further information
17:00 - 18:00 Key note speaker: Professor Jes Olesen
The burden of brain diseases in Europe - a challenge for clinical and basic research initiatives
18:00 - 19:00Reception

Day 1 Monday 15.08.05

Schizophrenia

Introduction and summary of clinical symptoms and definitionsBirte Glenthøj, DK
Current research trends - an overviewDaniel Weinberger, USA
The neurodevelopmental hypothesis in the era of genetic enlightenmentDaniel Weinberger, USA
Schizophrenia Genes: Susceptibility to whatRobin Murray, UK
Novel antipsychotics and underlying mechanisms of actionTorgny Svensson, S
Round Table 
Genes, Development and the Monoamine-hypothesisIntroduction by Kjeld Møllgård, DK
(including Kari Stefansson, IS in addition to the today's speakers)

Day 2 Tuesday 16.08.05

Genetic approaches in psychiatry

Introduction and current research trends - an overviewOle Kjærulff, DK
Transgenic mouse models for cerebral cortex development and schizophrenia pathogenesisNiels Aagaard Jensen, DK
Genes, neurotrophins and neuropsychiatric disordersEreo Castrén, FIN
Blood of the Vikings: The hunt for disease genes in the Icelandic populationKari Stefansson, IS
Round Table 

Day 3 Wednesday 17.08.05

Drug dependence

Introduction and current research trends - an overviewDavid Woldbye, DK
Transmitters, receptor systems and gene expression in drug dependenceWalter Zieglgänsberger, D
Abuse-related effects of cocaine in rodents: roles of dopaminergic and related systemsBarak Caine, US
Nicotine addiction and the dopaminergic reward pathwayTorgny Svensson, S
Clinical alcohol research today and in the future Jakob Ulrichsen, DK
Round table 

Day 4 Thursday 18.08.05

Depression and mania

Introduction and Current research trends - an overviewLars Vedel Kessing, DK
Depression and the immune systemBrian Leonard, Ireland
Mouse models of depression in the post genomic era: Recent developments and future needsJohn F. Cryan, CH
Electroconvulsive seizures and neurogenesisAnders Tingström, S
Round table 

Day 5 Friday 19.08.05

Epilepsy: from neuron to seizure

Introduction and Current research trends an overviewDavid Woldbye, DK
Current research trends concerning the nosology of the epilepsiesPeter Wolf, DK
Synaptic networks in experimental temporal lobe epilepsyJG Jefferys, UK
The role of neurotrophic factors and neuropeptides in temporal lobe epilepsyMerab Kokaia, S
Patophysiology of status epilepticusUwe Heinemann, D
Round table 

Day 6 Monday 22.08.05

Amyotrophic Lateral Sclerosis

IntroductionPeter M Andersen, S
What is ALS? Clinical Symtoms, Diagnosis, NeurophysiologyMarkus Weber, CH
Neuropathology and neuropathogenesis of ALSPaul Ince, UK
On the origin of ALS: Genetics, soccer, war and the environmentPeter M Andersen, S
Treatment of ALS incl. Clinical TrialsMarkus Weber, CH
Stem Cells and ALS: Is there a future? Vincenzo Silani, I
Round table 

Day 7 Tuesday 23.08.05

Neurodegenerative diseases, specially those involving trinucleotide repeats

The PolyQ diseases - Introduction and current trendsLis Hasholt, DK
Clinical and molecular aspects of the hereditary cerebellar ataxiasJørgen E. Nielsen, DK
The mechanisms of PolyQ diseasesKenneth Fischbeck, USA
Mouse models for Huntington's disease Maria Björkqvist, S
Application of microarray technology to experimental neurologySergey Anisimov, S
Round table 

Day 8 Wednesday 24.08.05

Multiple Sclerosis

Introduction and current research trendsPer Soelberg Sørensen, DK
Genetic epidemiology of multiple sclerosisGeorge C. Ebers, UK
How the brain repairs itself? A new immunobiological view of MS pathogenesisGianvito Martino, I
Recent advances in our understanding of MS immunology and the bases of immunomodulatory therapyHans-Peter Hartung, D
New perspectives in MS therapyLudwig Kappos, CH
Round table

Acta Physiologica Scandinavia Symposium

Title: Plasticity and regeneration of the spinal cord and peripheral nervous system


Day 8 Wednesday 24.08.05

Normal spinal cord function

Welcome and introductionJens Bo Nielsen, DK
Locomotion in the adult catHans Hultborn, DK
The C3-C4 propriospinal system for reaching and food taking Bror Alstermark, S
Spinal cord function in manJens Bo Nielsen, DK

Day 9 Thursday 25.08.05

Spinal cord pathophysiology: Spasticity

Mouse models: Receptor mutations for the glycine receptorCord-Michael Becker, D
Hyperekplexia - startle & stiffnessGert van Dijk, Leiden, NL
Hereditary spastic paraparesisJørgen E. Nielsen, DK
Plateau potentials in motoneurons and development of spasticityHans Hultborn, DK
General discussion 
Changes in spinal reflex transmission in various forms of clinical spasticityJens Bo Nielsen / Clarissa Crone, DK

Spinal cord plasticity

Plasticity in the rat spinal cordJens Schouenborg, S (reply pending)
Spinal reflex plasticity and motor learningJonathan Wolpaw, USA
Changes in transmission in the C3-C4 propriospinal system following spinal cord injuryLars-Gunnar Pettersson, S
General discussion 

Day 10 Friday 26.08.05

Spinal cord injury and repair

Evaluation of spinal cord function in spinal cord injured patientsPeter Ellaway, UK
Cell transplantation for spinal cord repair: advantages and limitationsJohn Riddell, Scotland
Glia transplantation for repair of the injured adult spinal cordMartin Oudega, USA

Degeneration and regeneration of peripheral nerves

Introduction and overview, with special emphasis on degeneration / regenerationChristian Krarup, DK
A mechanism for axonal degeneration and strategy for axonal protectionKen Smith, UK
Factors that influence nerve generationChristian Krarup, DK
The specificity of nerve regeneration (preferential reinnervation)Roger Madison, USA
Recovery of function and structure after regenerationMihai Moldovan, DK
Hand function following peripheral nerve generationGöran Lundborg, S
Final discussion 
Symposium dinner 

Symposium dinner