
Preliminary program Baltic Summer School 2009
University of Kiel
Sunday, September 6 th :
| 13:00 – 17:00: | Registration |
| 17:00 – 18:30 | Welcome addresses and honorary lecture – open for public |
| 19:00 – 21:00: | Get together |
07.09. – 11.09.2009 (Monday – Friday): daily sessions
14.09. – 18.09.2009 (Monday – Friday): daily sessions
21.09. – 25.09.2009 (Monday – Friday): lab – course
| Day 1 (07.09.09) | |||
| General topic:Basic principles: Genetic and non–genetic risk factors for complex disease | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Genetic and non–genetic aspects of asthma. | Ivo Gut |
| 9.45 – 10.30 | Lecture | The importance of rare variants vs. common variants – what have we learnt from GWAS and what can we get with next generation sequencing? | David Clayton |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Statistical concerns and approaches for complex disease genetics. | Thomas Wienker |
| 11.45 – 12.30 | Lecture | Goals and scientific visions of disease genome research in Asia. | Jun Wang |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | Global mapping of copy–number variants in humans by next generation sequencing. | Jan Korbel |
| 15.15 – 16.00 | Lecture | The Wellcome Trust Case Control Consortium 2 Study. | Jeffrey Barrett |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| 19.30 | Evening–Lecture | Throughput sequencing and microbial forensics. | Bruce Budowle |
| Day 2 (08.09.09) | |||
| General topic:Molecular technology for disease gene discovery | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | The Neandertal genome and the reconstruction of the ancestral human proteome. | Hernán A. Burbano |
| 9.45 – 10.30 | Lecture | Sequencing individual human genomes by massively parallel ligation chemistry. | Francisco de la Vega |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Nanoscience and genomics | Kalim Mir |
| 11.45 – 12.30 | Lecture | 3rd Generation Sequencing II | Marcus Dröge |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | Reduction of genomic complexity – enrichment strategies. | Olle Ericsson | 15.15 – 16.00 | Lecture | Genetics of primary sclerosing cholangitis, a role model for an inflammatory, HLA–associated disease. | Tom Hemming Karlsen |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| Day 3 (09.09.09) | |||
| General topic:Genetic risk factors in inflammatory barrier disease | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Molecular Dissection of Psoriasis: Integrating Genetics and Biology. | James T. Elder |
| 9.45 – 10.30 | Lecture | Risk map of intestinal inflammatory disorders. | Cisca Wijmenga |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Asthma genetics. | Michael Kabesch |
| 11.45 – 12.30 | Lecture | Genetics susceptibility factors for atopic eczema. | Stephan Weidinger |
| 12.30 – 14.30 | Lunch | ||
| 14.30 15.15 | Lecture | A genome–wide perspective of genetic variation in human metabolism. | Thomas Illig |
| 15.15 – 16.00 | Lecture | Genetic risk factors for Coronary heart disease (CHD). | Heribert Schunkert |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| Day 4 (10.09.09) | |||
| General topic:Genomic discovery of disease mechanisms and non–genetic trigger factors | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Gene mining for novel biocatalysts in marine microbial communities. | Ruth Schmitz–Streit |
| 9.45 – 10.30 | Lecture | The human intestinal microbiome project – present and future(Cluster lecture – Inflammation at interfaces). | Daniel Frank |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Microbiota and mucosal disease. | Stephan Ott |
| 11.45 – 12.30 | Lecture | Functional genomics in neuroblastoma. | Alexander Schramm |
| 12.30 – 14.30 | Lunch | ||
| 14.30 15.15 | Lecture | Host microbial responses in the gastrointestinal tract. | Frederik Bäckhed |
| 15.15 – 16.00 | Lecture | Genetics, genomics and systems biology. | Hans Lehrach |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| Day 5 (11.09.09) | |||
| General topic:Molecular principles of ageing | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Epidemiology and demography of human longevity. | Jutta Gampe |
| 9.45 – 10.30 | Lecture | Genetics of human longevity. | Claudio Franceschi |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Model organisms for ageing research: C. elegans. | Hinrich Schulenburg |
| 11.45 – 12.30 | Lecture | Model organisms for ageing research: from drosophila to mouse. | Matthias Platzer |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | System biology and ageing. | Tom Kirkwood |
| 15.15 – 16.00 | Lecture | Ageing and homeostasis. | James Adjaye |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| Day 6 (14.09.09) | |||
| General topic:Epigenetic disease mechanisms | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Methodological Review | Where epigenomics meet diagnostics. | Jörn Lewin |
| 9.45 – 10.30 | Lecture | Mechanisms and patterns of epimutations in cancer. | Heinz Linhart |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Heterochromatin, epigenetic inheritance and cancer. | Prim Singh |
| 11.45 – 12.30 | Lecture | Imprinting disorders. | Bernhard Horsthemke |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | Reverse phenotyping: towards an integrated (epi)genomic approach to complex phenotypes and common disease. | Stephan Beck |
| 15.15 – 16.00 | Lecture | Epigenetic changes in cancer. | Reiner Siebert |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| 19.30 | Evening–Lecture | Advances in genomics of human gene expression. | Emmanouil Dermitzakis |
| Day 7 (15.09.09) | |||
| General topic:Pathway mapping | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Reverse engineering of disease mechanisms. | Vitor dos Santos |
| 9.45 – 10.30 | Lecture | Modelling biological systems using genomic and proteomic data. | Ruprecht Kuner |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Protein interaction maps – pathways and beyond. | Stefan Wiemann |
| 11.45 – 12.30 | Lecture | Systematic RNAi approaches – how to design follow up hits from RNAi screens. | Frank Bucholz |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | System biology of apoptosis. | Inna Lavrik |
| 15.15 – 16.00 | Lecture | Regulatory networks characterize cellular identities. | Franz Josef Müller |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| Day 8 (16.09.09) | |||
| General topic:Bringing genetics to medicine diagnostic and therapeutic applications | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Implication of pharmacogenomics in drug therapy – chances and limitations. | Ingolf Cascorbi |
| 9.45 – 10.30 | Lecture | Polymorphisms in innate immune receptors in transplantation medicine. | Ernst Holler |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Molecular diagnostics in leukemia – a guide to individualized treatment? | Martin Schrappe |
| 11.45 – 12.30 | Lecture | Genomic insights into solid tumors – from bench to bedside. | Roman Thomas |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | Gene therapy in cardiovascular disease. | Norbert Frey |
| 15.15 – 16.00 | Lecture | Rationale drug design in important pathways – the story of gp130. | Stefan Rose–John |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| 19.30 | Evening–Lecture | Genetics risk map of inflammatory bowel disease. | Christoper Mathew |
| Day 9 (17.09.09) | |||
| General topic:Ethical aspects of genetic medicine | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Review | Predictive value of DTC tests and their usefulness. | Cecile Janssens |
| 9.45 – 10.30 | Lecture | Ethics in biobankings / Informed consent. | Michael Krawczak |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Enabling responsible public genomics. | Daniel Vorhaus |
| 11.45 – 12.30 | Lecture | Community genetics – from bench to bedside use of research results in clinical genetics. | Ulf Kristofferson |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | Public health economics and genetics. | Wolf Rogowski |
| 15.15 – 16.00 | Lecture | Genes: ethical dimensions of prediction, prevention and personalization. | Norbert Paul |
| 16.00 – 16.30 | Break | ||
| 16.30 – 17.30 | Round table | All Speakers | |
| Day 10 (18.09.09) | |||
| General topic:Transgenic or provocation animal models – which way to go | |||
| 8.50 – 9.00 | Introduction | ||
| 9.00 – 9.45 | Lecture | Endoplasmatic reticulum stress and inflammation. | Arthur Kaser |
| 9.45 – 10.30 | Lecture | Tumor models in laboratory animals. | Manolis Pasparakis |
| 10.30 – 11.00 | Break | ||
| 11.00 – 11.45 | Lecture | Gene function annotation using various mutagenesis strategies. | Ralf Kühn |
| 11.45 – 12.30 | Lecture | The German Mouse Clinic – running an open access mouse clinic. | Valerie Gailus–Durner |
| 12.30 – 14.30 | Lunch | ||
| 14.30 – 15.15 | Lecture | Combining provocation with transgenic models – an immunological perspective. | Massimo Fantini |
| 15.15 – 16.00 | Lecture | Molecular population genetics and wild mice as tools to understanding the evolution of disease genes. | John Baines |
| 16.00 – 16.30 | Closing Remarks | Philip Rosenstiel | |